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Text File | 1994-11-23 | 13.9 KB | 200 lines | [TEXT/TPAS]

LOCUS HUMIL1BX 9721 bp ds-DNA PRI 15-JUN-1988 DEFINITION Human interleukin 1 beta gene. ACCESSION X04500 SOURCE ORGANISM Homo sapiens REFERENCE 1 AUTHOR Clark,B.D., Collins,K.L., Gandy,M.S., Webb,A.C. and Auron,P.E. JOURNAL Nucleic Acids Res. 14, 7897-7914 (1986) STANDARD simple FEATURES from to/span description pept 2481 2527 prointerleukin-1-beta, exon 2 ( first expressed exon) /nomgen="IL1" /map="2q13-q21" 3092 3143 prointerleukin-1-beta, exon 3 5125 5326 prointerleukin-1-beta, exon 4 5874 6038 prointerleukin-1-beta, exon 5 7275 7405 prointerleukin-1-beta, exon 6 8127 8339 prointerleukin-1-beta, exon 7 pre-msg 1934 8941 IL mRNA and introns IVS 2006 2465 IL intron A IVS 2528 3091 IL intron B IVS 3144 5124 IL intron C IVS 5327 5873 IL intron D IVS 6039 7274 IL intron E IVS 7406 8126 IL intron F rpt 656 668 Alu repeat copy A 5' flank rpt 669 960 Alu repeat copy A rpt 961 971 Alu repeat copy A 3' flank rpt 4642 4658 Alu repeat copy B 5' flank rpt 4659 4988 Alu repeat copy B rpt 4989 5007 Alu repeat copy B 3' flank rpt 9251 9721 Alu repeat copy C refnumbr 1934 1934 numbered 1 in [1]; zero not used BASE COUNT 2661 a 2328 c 2122 g 2608 t 2 others ORIGIN 1 agaaagaaag agagagagaa agaaaagaaa gaggaaggaa ggaaggaagg aagaaagaca 61 ggctctgagg aaggtggcag ttcctacaac gggagaacca gtggttaatt tgcaaagtgg 121 atcctgtgga ggcanncaga ggagtcccct aggccaccca gacagggctt ttagctatct 181 gcaggccaga caccaaattt caggagggct cagtgttagg aatggattat ggcttatcaa 241 attcacagga aactaacatg ttgaacagct tttagatttc ctgtggaaaa tataacttac 301 taaagatgga gttcttgtga ctgactcctg atatcaagat actgggagcc aaattaaaaa 361 tcagaaggct gcttggagag caagtccatg aaatgctctt tttcccacag tagaacctat 421 ttccctcgtg tctcaaatac ttgcacagag gctcactccc ttggataatg cagagcgagc 481 acgatacctg gcacatacta atttgaataa aatgctgtca aattcccatt cacccattca 541 agcagcaaac tctatctcac ctgaatgtac atgccaggca ctgtgctaga cttggctcaa 601 aaagatttca gtttcctgga ggaaccagga gggcaaggtt tcaactcagt gctataagaa 661 gtgttacagg ctggacacgg tggctcacgc ctgtaatccc aacatttggg aggccgaggc 721 gggcagatca caaggtcagg agatcgagac catcctggct aacatggtga aaccctgtct 781 ctactaaaaa tacaaaaaat tagccgggcg ttggcggcag gtgcctgtag tcccagctgc 841 tggggaggct gaggcaggag aatggtgtga acccgggagg cggaacttgc agggggccga 901 gatcgtgcca ctgcactcca gcctgggcga cagagtgaga ctctgtctca aaaaaaaaaa 961 aaaagtgtta tgatgcagac ctgtcaaaga ggcaaaggag ggtgttccta cactccaggc 1021 actgttcata acctggactc tcattcattc tacaaatgga gggctcccct gggcagatcc 1081 ctggagcagg cactttgctg gtgtctcggt taaagagaaa ctgataactc ttggtattac 1141 caagagatag agtctcagat ggatattctt acagaaacaa tattcccact tttcagagtt 1201 caccaaaaaa tcattttagg cagagctcat ctggcattga tctggttcat ccatgagatt 1261 ggctagggta acagcacctg gtcttgcagg gttgtgtgag cttatctcca gggttgcccc 1321 aactccgtca ggagcctgaa ccctgcatac cgtatgttct ctgccccagc caagaaaggt 1381 caattttctc ctcagaggct cctgcaattg acagagagct cccgaggcag agaacagcac 1441 ccaaggtaga gacccacacc ctcaatacag acagggaggg ctattggccc ttcattgtac 1501 ccatttatcc atctgtaagt gggaagattc ctaaacttaa gtacaaagaa gtgaatgaag 1561 aaaagtatgt gcatgtataa atctgtgtgt cttccacttt gtcccacata tactaaattt 1621 aaacattctt ctaacgtggg aaaatccagt attttaatgt ggacatcaac tgcacaacga 1681 ttgtcaggaa aacaatgcat atttgcatgg tgatacattt gcaaaatgtg tcatagtttg 1741 ctactccttg cccttccatg aaccagagaa ttatctcagt ttattagtcc cctcccctaa 1801 gaagcttcca ccaatactct tttccccttt cctttaactt gattgtgaaa tcaggtattc 1861 aacagagaaa tttctcagcc tcctacttct gcttttgaaa gctataaaaa cagcgaggga 1921 gaaactggca gataccaaac ctcttcgagg cacaaggcac aacaggctgc tctgggattc 1981 tcttcagcca atcttcattg ctcaagtatg actttaatct tccttacaac taggtgctaa 2041 gggagtctct ctgtctctct gcctctttgt gtgtatgcat attctctctc tctctctctt 2101 tctttctctg tctctcctct ccttcctctc tgcctcctct ctcagctttt tgcaaaaatg 2161 ccaggtgtaa tataatgctt atgactcggg aaatattctg ggaatggata ctgcttatct 2221 aacagctgac accctaaagg ttagtgtcaa agcctctgct ccagctctcc tagccaatac 2281 attgctagtt ggggtttggt ttagcaaatg cttttctcta gacccaaagg acttctcttt 2341 cacacattca ttcatttact cagagatcat ttctttgcat gactgccatg cactggatgc 2401 tgagagaaat cacacatgaa cgtagccgtc atggggaagt cactcatttt ctccttttta 2461 cacaggtgtc tgaagcagcc atggcagaag tacctgagct cgccagtgaa atgatggctt 2521 attacaggtc agtggagacg ctgagaccag taacatgagc aggtctcctc tttcaagagt 2581 agagtgttat ctgtgcttgg agaccagatt tttcccctaa attgcctctt tcagtggcaa 2641 acagggtgcc aagtaaatct gatttaaaga ctactttccc attacaagtc cctccagcct 2701 tgggacctgg aggctatcca gatgtgttgt tgcaagggct tcctgcagag gcaaatgggg 2761 agaaaagatt ccaagcccac aatacaagga atccctttgc aaagtgtggc ttggagggag 2821 agggagagct cagattttag ctgactctgc tgggctagag gttaggcctc aagatccaac 2881 agggagcacc agggtgccca cctgccaggc ctagaatctg ccttctggac tgttctgcgc 2941 atatcactgt gaaacttgcc aggtgtttca ggcagctttg agaggcaggc tgtttgcagt 3001 ttcttatgaa cagtcaagtc ttgtacacag ggaaggaaaa ataaacctgt ttagaagaca 3061 taattgagac atgtccctgt ttttattaca gtggcaatga ggatgacttg ttctttgaag 3121 ctgatggccc taaacagatg aaggtaagac tatgggttta actcccaacc caaggaaggg 3181 ctctaacaca gggaaagctc aaagaaggga gttctgggcc actttgatgc catggtattt 3241 tgttttagaa agactttaac ctcttccagt gagacacagg ctgcaccact tgctgacctg 3301 gccacttggt catcatatca ccacagtcac tcactaacgt tggtggtggt ggccacactt 3361 ggtggtgaca ggggaggagt agtgataatg ttcccatttc atagtaggaa gacaaccaag 3421 tcttcaacat aaatttgatt atccttttaa gagatggatt cagcctatgc caatcacttg 3481 agttaaactc tgaaaccaag agatgatctt gagaactaac atatgtctac cccttttgag 3541 tagaatagtt ttttgctacc tggggtgaag cttataacaa caagacatag atgatataaa 3601 caaaaagatg aattgagact tgaaagaaaa ccattcactt gctgtttgac cttgacaagt 3661 cattttaccc gctttggacc tcatctgaaa aataaagggc tgagctggat gatctctgag 3721 attccagcat cctgcaacct ccagttctga aatattttca gttgtagcta agggcatttg 3781 ggcagcaaat ggtcattttt cagactcatc cttacaaaga gccatgttat attcctgctg 3841 tcccttctgt tttatatgat gctcagtagc cttcctaggt gcccagccat cagcctagct 3901 aggtcagttg tgcaggttgg aggcagccac ttttctctgg ctttatttta ttccagtttg 3961 tgatagcctc ccctagcctc ataatccagt cctcaatctt gttaaaaaca tatttcttta 4021 gaagttttaa gactggcata acttcttggc tgcagctgtg ggaggagccc attggcttgt 4081 ctgcctggcc tttgcccccc attgcctctt ccagcagctt ggctctgctc caggcaggaa 4141 attctctcct gctcaacttt cttttgtgca cttacaggtc tctttaactg tctttcaagc 4201 ctttgaacca ttatcagcct taaggcaacc tcagtgaagc cttaatacgg agcttctctg 4261 aataagagga aagtggtaac atttcacaaa aagtactctc acaggatttg cagaatgcct 4321 atgagacagt gttatgaaaa aggaaaaaaa agaacagtgt agaaaaattg aatacttgct 4381 gagtgagcat aggtgaatgg aaaatgttat ggtcatctgc atgaaaaagc aaatcatagt 4441 gtgacagcat tagggataca aaaagatata gagaaggtat acatgtatgg tgtaggtggg 4501 gcatgtacaa aaagatgaca agtagaatcg ggatttattc taaagaatag cctgtaaggt 4561 gtccagaagc cacattctag tcttgagtct gcctctacct gctgtgtgcc cttgagtaca 4621 cccttaacct ccttgagctt cagagaggga taatcttttt attttatttt attttatttt 4681 gttttgtttt gttttgtttt gttttatgag acagagtctc actctgttgc ccaggctgga 4741 gtgcagtggt acaatcttgg cttactgcat cctccacctc ctgagttcaa gcgattctcc 4801 ttcctcagtc tcctgaatag ctaggattac aggtgcaccc caccacaccc agctaatttt 4861 tgtattttta gtagagaagg ggtttcgcca tgttggccag gctggttttg aagtcctgac 4921 ctaaatgatt catccacctc ggcttcccaa agtgctggga ttacaggcat gagccaccac 4981 gcctggccca gagagggatg atctttagaa gctcgggatt ctttcaagcc ctttcctcct 5041 ctctgagctt tctactctct gatgtcaaag catggttcct ggcaggacca cctcaccagg 5101 ctccctccct cgctctctcc gcagtgctcc ttccaggacc tggacctctg ccctctggat 5161 ggcggcatcc agctacgaat ctccgaccac cactacagca agggcttcag gcaggccgcg 5221 tcagttgttg tggccatgga caagctgagg aagatgctgg ttccctgccc acagaccttc 5281 caggagaatg acctgagcac cttctttccc ttcatctttg aagaaggtag ttagccaaga 5341 gcaggcagta gatctccact tgtgtcctct tggaagtcat caagccccag ccaactcaat 5401 tcccccagag ccaaagccct ttaaaggtag aaggcccagc ggggagacaa aacaaagaag 5461 gctggaaacc aaagcaatca tctctttagt ggaaactatt cttaaagaag atcttgatgg 5521 ctactgacat ttgcaactcc ctcactcttt ctcaggggcc tttcacttac attgtcacca 5581 gaggttcgta acctccctgt gggctagtgt tatgaccatc accattttac ctaagtagct 5641 ctgttgctcg gccacagtga gcagtaatag acctgaagct ggaacccatg tctaatagtg 5701 tcaggtccag tgttcttagc caccccactc ccagcttcat ccctactggt gttgtcatca 5761 gactttgacc gtatatgctc aggtgtcctc caagaaatca aattttgcca cctcgcctca 5821 cgaggcctgc ccttctgatt ttatacctaa acaacatgtg ctccacattt cagaacctat 5881 cttcttcgac acatgggata acgaggctta tgtgcacgat gcacctgtac gatcactgaa 5941 ctgcacgctc cgggactcac agcaaaaaag cttggtgatg tctggtccat atgaactgaa 6001 agctctccac ctccagggac aggatatgga gcaacaaggt aaatggaaac atcctggttt 6061 ccctgcctgg cctcctggca gcttgctaat tctccatgtt ttaaacaaag tagaaagtta 6121 atttaaggca aatgatcaac acaagtgaaa aaaaatatta aaaaggaata tacaaacttt 6181 ggtcctagaa atggcacatt tgattgcact ggccagtgca tttgttaaca ggagtgtgac 6241 cctgagaaat tagacggctc aagcactccc aggaccatgt ccacccaagt ctcttgggca 6301 tagtgcagtg tcaattcttc cacaatatgg ggtcatttga tggacatggc ctaactgcct 6361 gtgggttctc tcttcctgtt gttgaggctg aaacaagagt gctggagcga taatgtgtcc 6421 atccccctcc ccagtcttcc ccccttgccc caacatccgt cccacccaat gccaggtggt 6481 tccttgtagg gaaattttac cgcccagcag gaacttatat ctctccgctg taacgggcaa 6541 aagtttcaag tgcggtgaac ccatcattag ctgtggtgat ctgcctggca tcgtgccaca 6601 gtagccaaag cctctgcaca ggagtgtggg caactaaggc tgctgacttt gaaggacagc 6661 ctcactcagg gggaagctat ttgctctcag ccaggccaag aaaatcctgt ttctttggaa 6721 tcgggtagta agagtgatcc cagggcctcc aattgacact gctgtgactg aggaagatca 6781 aaatgagtgt ctctctttgg agccactttc ccagctcagc ctctcctctc ccagtttctt 6841 cccatgggct actctctgtt cctgaaacag ttctggtgcc tgatttctgg cagaagtaca 6901 gcttcacctc tttcctttcc ttccacattg atcaagttgt tccgctcctg tggatgggca 6961 cattgccagc cagtgacaca atggcttcct tccttccttc cttcagcatt taaaatgtag 7021 accctctttc attctccgtt cctactgcta tgaggctctg agaaaccctc aggcctttga 7081 ggggaaaccc taaatcaaca aaatgaccct gctattgtct gtgagaagtc aagttatcct 7141 gtgtcttagg ccaaggaacc tcactgtggg ttcccacaga ggctaccaat tacatgtatc 7201 ctactctcgg ggctaggggt tggggtgacc ctgcatgctg tgtccctaac cacaagaccc 7261 ccttctttct tcagtggtgt tctccatgtc ctttgtacaa ggagaagaaa gtaatgacaa 7321 aatacctgtg gccttgggcc tcaaggaaaa gaatctgtac ctgtcctgcg tgttgaaaga 7381 tgataagccc actctacagc tggaggtaag tgaatgctat ggaatgaagc ccttctcagc 7441 ctcctgctac cacttattcc cagacaattc accttctccc cgcccccatc cctaggaaaa 7501 gctgggaaca ggtctatttg acaagttttg cattaatgta aataaattta acataatttt 7561 taactgcgtg caaccttcaa tcctgctgca gaaaattaaa tcattttgcc gatgttatta 7621 tgtcctacca tagttacaac cccaacagat tatatattgt tagggctgct ctcatttgat 7681 agacaccttg ggaaatagat gacttaaagg gtcccattat cacgtccact ccactcccaa 7741 aatcaccacc actatcacct ccagctttct cagcaaaagc ttcatttcca agttgatgtc 7801 attctaggac cataaggaaa aatacaataa aaagcccctg gaaactaggt acttcaagaa 7861 gctctagctt aattttcacc cccccaaaaa aaaaaaattc tcacctacat tatgctcctc 7921 agcatttggc actaagtttt agaaaagaag aagggctctt ttaataatca cacagaaagt 7981 tgggggccca gttacaactc aggagtctgg ctcctgatca tgtgacctgc tcgtcagttt 8041 cctttctggc caacccaaag aacatctttc ccataggcat ctttgtccct tgccccacaa 8101 aaattcttct ttctctttcg ctgcagagtg tagatcccaa aaattaccca aagaagaaga 8161 tggaaaagcg atttgtcttc aacaagatag aaatcaataa caagctggaa tttgagtctg 8221 cccagttccc caactggtac atcagcacct ctcaagcaga aaacatgccc gtcttcctgg 8281 gagggaccaa aggcggccag gatataactg acttcaccat gcaatttgtg tcttcctaaa 8341 gagagctgta cccagagagt cctgtgctga atgtggactc aatccctagg gctggcagaa 8401 agggaacaga aaggtttttg agtacggcta tagcctggac tttcctgttg tctacaccaa 8461 tgcccaactg cctgccttag ggtagtgcta agaggatctc ctgtccatca gccaggacag 8521 tcagctctct cctttcaggg ccaatcccca gcccttttgt tgagccaggc ctctctcacc 8581 tctcctactc acttaaagcc cgcctgacag aaaccacggc cacatttggt tctaagaaac 8641 cctctgtcat tcgctcccac attctgatga gcaaccgctt ccctatttat ttatttattt 8701 gtttgtttgt tttgattcat tggtctaatt tattcaaagg gggcaagaag tagcagtgtc 8761 tgtaaaagag cctagttttt aatagctatg gaatcaattc aatttggact ggtgtgctct 8821 ctttaaatca agtcctttaa ttaagactga aaatatataa gctcagatta tttaaatggg 8881 aatatttata aatgagcaaa tatcatactg ttcaatggtt ctgaaataaa cttcactgaa 8941 gaaaaaaaaa aaagggtctc tcctgatcat tgactgtctg gattgacact gacagtaagc 9001 aaacaggctg tgagagttct tgggactaag cccactcctc attgctgagt gctgcaagta 9061 cctagaaata tccttggcca ccgaagacta tcctcctcac ccatcccctt tatttcgttg 9121 ttcaacagaa ggatattcag tgcacatctg gaacaggatc agctgaagca ctgcagggag 9181 tcaggactgg tagtaacagc taccatgatt tatctatcaa tgcaccaaac atctgttgag 9241 caagcgctat gtactaggag ctgggagtac agagatgaga acagtcacaa gtccctcctc 9301 agataggaga ggcagctagt tataagcaga acaaggtaac atgacaagta gagtaagata 9361 gaagaacgaa gaggagtagc caggaaggag ggaggagaac gacataagaa tcaagcctaa 9421 agggataaac agaagatttc cacacatggg ctgggccaat tgggtgtcgg ttacgcctgt 9481 aatcccagca ctttgggtgg caggggcaga aagatcgctt gagcccagga gttcaagacc 9541 agcctgggca acatagtgag actcccatct ctacaaaaaa taaataaata aataaaacaa 9601 tcagccaggc atgctggcat gcacctgtag tcctagctac ttgggaagct gacactggag 9661 gattgcttga gcccagaagt tcaagactgc agtgagctta tccgttgacc tgcaggtcga 9721 c //